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Body Surface Area (Meters Squared) DuBois & DuBois Formula
Enter Dosage Interval (hours)
Calculated Trough (mcg/ml)Maximum for Pulse Dosing: Amikacin 0.9 mcg/ml Gentamicin/Tobramycin 0.3 mcg/ml
Time (hours) to 87.5% of Steady State from first dose (assuming no loading dose)
Area Under the Curve mg*h/L per dayAmikacin: Pulse Dosing 15 mg/kg of dosing weight Maximum AUC 380 mg*h/L per dayGentamicin/Tobramycin: Pulse Dosing 5 mg/kg of dosing weight Maximum AUC 127 mg*h/L per day Pulse Dosing 7 mg/kg of dosing weight Maximum AUC 172 mg*h/L per day Vancomycin AUC of 400-600 mg*h/L Monitor AUC for vancomycin with a peak and trough after the same dose and use the peak and trough dosing calculator as the accuracy of the AUC calculation is improved.
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